Fall Out

Draft your static blog page & sidebar copy in this area. The blog is where you can address all the other issues you wanted to talk about on the website:

  1. Video graphics to illustrate difficult concepts

  2. Infections result in autoimmunity

  3. Infections results in neuropsychiatric symptoms- PANDAS

  4. Infections can result in mysterious medical symptoms – which is 33% of the patients doctors see now – people with “mysterious symptoms” that they don’t know what to do with

  5. Infections can result in the symptoms of well-known medical diseases

  6. Addiction is autoimmune

  7. Psychiatry is autoimmune

  8. School shooters have PANDAS – medical history and story on them from a different perspective – each one of them – a timeline – and history – this will take a while

  9. The juvenile justice systems and prisons are overrun with infected individuals

  10. Targeting prevention rather than blame

    1. Different intakes

    2. A new way to do the mobile crisis unit

    3. A new way to treat psychiatric patients

      1. Psych meds are immunosuppressant

    4. A new way to treat addition – which comprises much of our prison system- most actually

  11. Medical kidnapping - DCS

Impact

What do

Addictions, School Shootings, Obesity, Divorce, and Medical Kidnapping

have to do with PANDAS/PANS?


Let’s be clear: We do not believe that everyone with PANDAS/PANS will ultimately be an addict, a school shooter, or more. Untreated PANDAS/PANS is dangerous, though, and you and your child are far better off if the PANDAS/PANS is diagnosed and treated swiftly.

PANDAS/PANS also is not the only factor at play in addictions, school shootings, obesity, divorce, medical kidnappings, and more. Chronic infections can be a factor in this complex puzzle, and if these infections are not properly treated, then whose fault is it when the infected person acts out? Is the person to blame, or is the infection?

Addiction

Addiction is a brain disorder not otherwise specified (NOS). We believe that addiction is a subset of obsessive-compulsive disorder (OCD) and that it is often—if not always—an autoimmune response. As such, addiction is either a stand-alone autoimmune disease, or it is a symptom of an underlying autoimmune process.

The ratio of girls to boys who overdose on heroin is 1:3. This is also the ratio of girls to boys who have PANDAS/PANS. Coincidence? We think not. We believe there is a connection between addiction and PANDAS/PANS. If this remains undiagnosed, it may evolve into one of our nation’s worst problems. It is time to start making accurate connections and nip this in the bud.

Addiction treatment trailblazer Michael T. Cartwright co-founded the American Addiction Centers, Inc. He is a third-generation sufferer of this psychosis NOS that results in “unexplained episodes.” We know these to be PANDAS/PANS flares, and they are likely to cause anyone to look to drugs or alcohol in an effort to quell the psychological symptoms.

An excerpt from his book, Believable Hope, chronicles his struggle with what appears to be undiagnosed PANDAS/PANS.

As an eighteen-year-old, I had gotten so delusional that one day I pulled my car into Nashville’s West End Catholic Church parking lot, and with the car in park, I simply sat there with my foot on the accelerator, afraid to let up on the pedal because I was convinced that if I did, a bomb would explode in the car. For a long time, I sat there with the engine revved, the throttle fully open, the car roaring loudly in the parking lot.

Finally, I mustered the courage to open the door and dive out of the vehicle. The engine immediately calmed to a quiet purr, and much to my surprise, the car did not blow up. I picked myself up off the pavement and stumbled toward the closest doors of the church. Once inside I found a priest and told him my story. He arranged for me to be seen by a doctor in Parthenon Pavilion Hospital, where the doctors diagnosed me with paranoid schizophrenia. I spent two weeks in the hospital. I left with a batch of prescriptions, but nothing else in my life had substantially changed.

Two years later, I broke again, this time in Florida. For a while, I had stayed off drugs and alcohol and had joined the military. When I entered the service, I checked off ‘no' on the form asking if I had any history of mental illness. I'm sorry now, but lying came all too naturally to me in those days. I had attended a military high school and was in good physical condition, so I doubt that anyone even checked into the details of my previous hospitalization. Later, I would be diagnosed with cyclic psychosis, a rare malady that mimics schizophrenia. My father suffered from a similar disease, as did my grandfather. Both men served their country well and had outstanding military careers, although they too found themselves in hospitals on more than one occasion, needing antipsychotic medications simply to bring them back to their baselines.

Perhaps because of their experience, I felt no qualms in signing up for the military.

I did well for about three months, and was preparing to attend Navy SEALs school, but then I became delusional and paranoid and had a psychotic break again. I felt as though I was in a scary movie, or a Vincent van Gogh painting; the walls were melting, people were talking about killing me. Everywhere I looked, people were trying to get me. I was catatonic; I couldn’t speak.

I was admitted to a psychiatric hospital in Orlando, and remained there for several months. I was in despair. Totally frayed and frazzled, I had suffered a psychotic break in which I felt as though somebody had poured battery acid over my brain. Exacerbating matters further, I was terrified because I couldn’t control my body’s responses.

The psychiatrists ordered a variety of heavy-duty medications designed to reduce my anxiety, but I was so delusional I refused to take the medication, because I was convinced that the drugs were poisoned. When my mom and a girlfriend finally convinced me to try the medication, rather than causing me to feel better, I felt worse. Now, I realized that I had been living in delusion for months. This is hell, I thought. I had no desire to get out of bed; I couldn't handle a menial job such as washing dishes at a restaurant or mowing lawns. I couldn't sit in a classroom or think clearly enough to take a class in school. The teacher's voice got garbled among the various other voices I was hearing, taunting me, talking to me and about me. I couldn't think, my words came out as gibberish. I didn't want to live like this.

I wanted to die.

When the doctors discharged me after five months, I walked out of the hospital with a stack of prescriptions, still feeling depressed and despondent, and still on heavy doses of antipsychotic medications.

It is important to note that Cartwright was treated with the antipsychotic medications Geodon and Zyprexa, the latter being the only psych med that children with PANDAS/PANS should be prescribed during flares. It’s a cytokine immunomodulator versus an immunosuppressant. The majority of all psych meds suppress the immune system and are unhealthy. It is important to eventually come off the medications once treatment is underway to allow the immune system to thrive.

Even Bob Smith, one of the founders of Alcoholics Anonymous, had suspicious medical problems (probably stemming from an infection in his gut).

Two Dry Quarters, Eight Dry Months

On the carpet once more, Bob was given a final chance. The dean of the medical school decided that if Bob wished to graduate, he needed to come back for two quarters, remaining completely dry. This he was able to accomplish, and in 1910, at age 31, he was finally Dr. Bob Smith.

City Hospital, Akron, Ohio

“I conducted myself so creditably that I was able to secure a much coveted internship in a western city, where I spent two years. During these two years I was kept so busy that I hardly left the hospital at all. Consequently, I could not get into any trouble.” (Nightmare, p. 174)

The new doctor opened an office downtown, in the Second National Bank Building, where he was to remain until he retired in 1948.

Perhaps as a result of the irregular hours and tense work of a new GP, Dr. Bob developed considerable stomach trouble. “I soon discovered that a couple of drinks would alleviate my gastric distress, at least for a few hours at a time,” he said. It didn’t take him long to return to the old drinking habits. Almost immediately, he began to “pay very dearly physically,” to know the real horror and suffering of alcoholism (Good Oldtimers, p. 28).

Mycoplasma has incomplete metabolic pathways and cannot break down protein. This creates an internal environment that causes cravings for simple sugars—including alcohol. Are the organisms exacerbating the symptoms of substance abuse disorder? Someone who is experiencing a misdirected immune response, which results in very uncomfortable symptoms, would feel tremendous relief with the suppression of their immune system. Opiates suppress the immune system… Is this what leads to someone becoming an addict? Is it possible that these pathogens drive us to do things we wouldn't normally do? Are they the “demons” we often hear about? Does removing alcohol from the equation slow the organism's growth so that people can seemingly recover? Proinflammatory cytokines found in the alcoholic human brain (He and Crews, 2008), increase the reward value of drinking alcohol in mice. US National Library of Medicine Notes

School Shootings

In each instance of a school shooting, the argument can be made the shooter could have been diagnosed with PANDAS/PANS. Here are just a couple that have been fairly obvious. Some of the other cases have to be dug into but the answers are readily available for those who are willing to look.

Grant Accord

"The West Albany High School student who was arrested last May after police found homemade bombs under his floorboards was sentenced Monday to 10 years in the custody of the Oregon Youth Authority as part of a plea agreement.

Grant Alan Acord, 17, admitted to six counts of manufacturing a destructive device and two counts of unlawful use of a weapon in juvenile court. The plea agreement dropped the adult charges that Acord faced, including a count of aggravated attempted murder. The charges for manufacturing a destructive device carry a five-year sentence, to be served consecutively with another five-year sentence for unlawful use of a weapon.

Albany police arrested Acord on May 23, 2013, after receiving a tip that Acord was planning an attack similar to the 1999 massacre of 12 students and one teacher at Columbine High School in Littleton, Colorado. Police found six homemade bombs in his bedroom and detailed written plans for an attack at West Albany.

Benton County District Attorney John Haroldson said the agreement took into account Acord's immaturity and the results of his psychological evaluations. He added that the principals of Albany's high schools supported the agreement, which will involve Acord receiving treatment through the juvenile system. After Acord's arrest, his mother, Marianne Fox, said her son suffers from a rare condition that can trigger obsessive-compulsive behavior.

Through her attorney, Fox said that Acord suffers from Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus (PANDAS)."

Gazette Times Article

YouTube Video

Adam Lanza

The Sandy Hook Elementary School shooting occurred on December 14, 2012, in Newtown, Connecticut, when 20-year-old Adam Lanza shot and killed 26 people, including 20 children between six and seven years old, and six adult staff members. Before driving to the school, he shot and killed his mother at their Newtown home. As first responders arrived at the school, Lanza committed suicide by shooting himself in the head.

"A recurring theme in this report [of Adam Lanza] is the struggle of a parent whose child has a severe disability to figure out how to alleviate his pain and protect him from stress and harm. When the parent has difficulties reaching out to helping providers or feels mistrust in the medical and educational systems, her efforts can become unwittingly destructive of the child's development and well-being. Our health care and educational systems must become better at reaching these parents and helping the children."

A neurological/developmental evaluation in early April 1997, just before AL's fifth birthday, noted that AL was an extremely active young child—he never slept through the night, continued to make up his own language, and reportedly did not like to be held, kissed or hugged. He was observed and reported to have odd repetitive behaviors and severe temper tantrums. AL was reported, at times, to ‘sit and hit his head repeatedly.' He did not tolerate touch or textures and refused to dress. Teachers reported AL was ‘very quiet during groups.'

Mrs. Lanza later told a friend that she was diagnosed with a ‘genetically flawed autoimmune disorder,' but that she intended to be discreet about her diagnosis so as to save loved ones ‘from unnecessary worry.' She asked her friend to keep her condition confidential. She continued to write about experiencing seizures, visiting a neurologist and ‘being tested, and poked, prodded, injected, and tortured.'"

There were no documented well-child visits between 11/24/03 and 9/11/06. In 2005 AL had numerous sick visits for sore throats, difficulty breathing, and marked weight loss. There is no documentation regarding follow up blood work or other evaluations to examine underlying causes for these symptoms, particularly the weight loss. AL's record indicates that he was seen for a variety of physical complaints over the years (chest pain, extremity pain, ear pain, eye pain, and repeated sore throat).

"His IEP team classified AL as eligible for special education with a primary disability of Other Health Impairment (rather than the more apt eligibility categories of Autism or Emotional Disturbance) and the IEP team created an education plan almost entirely without reference to AL's social emotional difficulties, except to say that his anxiety disorder, Asperger Syndrome, compulsive disorder, and rigidity impacted his learning in a regular education environment as well as his ability to take part in a general education curriculum."

"AL's pediatric records from age 13 to 17 note his obsessive compulsive behaviors, markedly underweight presentation, psychiatric diagnoses, and repeated homebound or independent study, but records don't clearly address AL's need for mental health treatment, and often note during high school years that no medication or psychiatric treatment was being provided..."

Report Of The Office Of The Child Advocate

"And from that point on, through his teens, the records suggest that his paralyzing obsessions, his raging germophobia that prevented him from touching door handles and other fixtures with a bare hand, and his rigid set of beliefs — not to mention the blacked-out windows of his bedroom and the countless hours he spent playing combat video games — would guarantee his place on the fringe.

His isolation had its roots in his developmental speech delays as a child, the first of a string of diagnoses that included obsessive-compulsive disorder, sensory integration deficit and autism spectrum disorder.

As a teenager, his sensory condition made him exceedingly sensitive to textures, sound, light and movement. He shunned his classmates, bothered by their choice of clothes and the noises they made. He cultivated a set of ground rules that fed his separateness.

Lanza's obsessive behavior is also described extensively in King's evaluation, obtained by the Courant. The report is a startling chronicle of severe obsessional behavior and dire warnings of what would happen to Lanza should there not be appropriate intervention.

In the report, King wrote, ‘Adam has a variety of rigid controlling and avoidant behaviors which have been loosely described as OCD but seem to have several facets.' Lanza had ‘the rigidity of a youngster with autistic spectrum disorder' plus ‘sensory defensiveness' and ‘classical obsessive-compulsive features.'"

L. A. Times Article

Although research is time consuming because of forging through uncharted territory, as you begin to recognize these patterns, the cases become easier to put together.

Michael Carneal

Paducah, KY - December 1, 1997- Killed 3 and wounded 5

"The thrust of Carneal's post-conviction motion is that he was misdiagnosed when evaluated following the crime.   Prior to his guilty plea, Carneal was evaluated by five mental health professionals, two of whom were hired by defense counsel.   All five concluded that Carneal was mentally competent at the time of the offense;  that is, he had the capacity to either appreciate the criminality of his conduct or to conform such conduct to the requirements of law.  KRS 504.020(1).   Their opinions of Carneal's mental condition, however, varied.   The Commonwealth's experts, who included two psychiatrists and one psychologist, submitted a combined report that indicated Carneal was maladjusted and prone to paranoia, anxiety, and depression.   The report offered no formal clinical diagnosis of a mental disorder.

The defense experts, Dr. Cornell and Dr. Schetky, diagnosed Carneal with schizotypal personality disorder and depression."

Possible Pans/Pandas Missed:

Schizotypal personality disorder can easily be confused with schizophrenia, a severe mental illness in which people lose contact with reality (psychosis). While people with schizotypal personality disorder may experience brief psychotic episodes with delusions or hallucinations, the episodes are not as frequent, prolonged or intense as in schizophrenia.

"Dr. Cornell and Dr. Schetky re-evaluated Carneal in 2004. Carneal claimed that, as a result of taking more powerful antipsychotic medication, his reality testing was greatly improved, and he was better able to convey details concerning his mental state in 1997 and 1998.   He recounted a history of psychotic symptoms, complex visual and auditory hallucinations, and paranoia that began about six months prior to the shootings.   He detailed his delusional thinking at the time of the crime and the auditory hallucinations that were directing his actions. Carneal explained that, at the time of his sentencing, he was unable to reveal the delusions because of threatening auditory hallucinations which he feared.

Based on these new revelations, Dr. Cornell and Dr. Schetky revised their previous diagnosis.   Dr. Schetky concluded that, at the time of the offense, Carneal was experiencing the onset of schizophrenia and was unable to reveal the extent of his delusions because he believed them to be true.   She concluded that Carneal lacked the substantial capacity to appreciate the criminality of his conduct, and that he was unable to conform his conduct to the requirements of the law because he was responding to command hallucinations.   In her 2004 evaluation, Dr. Schetky did not offer any opinion about Carneal's competency to stand trial in 1998.

Dr. Cornell, likewise, revised his diagnosis to one of full-blown schizophrenia.   He stated that "had I known of [Carneal's] auditory hallucinations and their effect on his judgment and behavior, I would have recommended that he be found incompetent to stand trial."   Further, Dr. Cornell concluded that "there is now sufficient evidence to support an insanity defense.""

Notes on the Supreme Court Case

Suicide

We believe that a majority of impulsive suicides could be a result of undiagnosed and untreated PANDAS/PANS. It is not difficult to make these connections once you ask the right questions.

Boy, 13, Takes Own Life On Christmas Eve. The Press Release I Was Not Prepared To Write

By Christine Wolf, January 6, 2017 at 2:02 am

Max Aaron Wallace (Becky Pate Wallace)

I've written only two press releases in my life, both in the past 4 months, both covering a set of pediatric autoimmune disorders called PANDAS & PANS.

Only one of those press releases -- this one -- brought me to my knees.

FOR IMMEDIATE RELEASE

CHICAGO, ILLINOIS – January 5, 2017 -- The national non-profit organization Pandas/Pans Advocacy & Support dedicates its 2017 Winter Grant Session in honor of Max Aaron Wallace of Benton, Arkansas. The 13-year-old took his own life on December 24, 2016, while suffering from an infection-triggered autoimmune disorder attacking the brain. Max's condition, commonly known as PANDAS or PANS (depending on its infectious source), is treatable.

Max's mother, Becky Pate Wallace, says her family struggled for years to get Max the proper diagnosis and treatment. He was scheduled to receive his first round of IVIG (intravenous immunoglobulin) therapy this month. IVIG is a complex blood product created from the serum of 1,000 to 15,000 human donors, used to "reset" the immune system in patients with antibody deficiencies.

"I want everyone to know we lack providers," says Max's mom, a health care provider. "We lack awareness, and we lack cooperation from our pediatricians. I want families to know we can no longer take ‘no' for an answer from our doctors."

Press Release

Maddy at 14

"From an early age, Maddy showed great promise as an athlete.

She played with boys on the Kennebecasis Valley Minor Hockey Association's Pee Wee AAA Rangers team and would later play for Rothesay Netherwood, an elite private school outside Saint John

.

At the age of 15, one of her highlights was to play on the U-18 Team Atlantic in Calgary for the Canadian Women's Nationals.

Maddy excelled in hockey and played for Team New Brunswick in Prince George, B.C., for the Canada Games in February 2015. (Mike Murphy/Facebook)

But at age 14, and seemingly overnight, Maddy developed symptoms of Tourette syndrome.

"She woke up and she just wasn't right," Mike said. "She was displaying tics and stuttering and couldn't talk."

He says his daughter felt ashamed and around this time, she started retreating from her parents and her sister and even her twin brother, to hole up in her room.

"We were walking on eggshells for quite a few years," Mike said.

"We knew that one wrong move would set her off and she would go into that deep, dark hole.""

Her tics may have subsided with immunosuppressive psych meds, but her PANDAS did not, and exposure to another infection was probably the unexpected culprit for the suicide.

"She seemed happy, says Mike, and her Tourette's tics had almost entirely subsided

.

Mindy says she still talked to her daughter almost every day.

Mindy and I thought she was doing really good [in college]," said Mike. "She seemed really happy. She was starting to get established in life."

Mike says that's why Maddy's decision to take her own life has shaken them to the core. They say they had no warning."

News Article

"Infection requiring hospitalization has been linked to a 43% increased risk of dying by suicide. The finding raises questions about the role of biological mechanisms of infection, particularly neuroinflammation, on suicidal behaviors.

The implication is that 1 in 10 suicides could be prevented if infections were to be eliminated entirely, provided that the association was causal," they write."

Medscape Article

We believe this number is significantly higher based on lack of testing, incompetence of several testing methods and lack of knowledge on behalf of practitioners regarding which organisms can cause suicide.

"Infection is one of the most common causes of illness in the world,1 and it is increasingly recognized that infection and inflammation can have a critical role in psychiatric disorders and in suicidal behavior. Suicide is a major health problem worldwide. However, while psychological predictors of suicide, such as psychiatric disorders and history of suicide attempts, have been examined extensively, there is a dearth of longitudinal studies investigating the effect of biological factors, such as infection."

"Although certain infectious agents infect the brain directly, others reach the brain from the periphery, and yet others generate molecular mediators of inflammation that cross from the periphery into the brain and thereby increase the risk of suicide. Examples of agents infecting the brain are influenza B virus and the parasite Toxoplasma gondii, which have been linked to suicidal behavior. In addition, an association between T gondii and phenotypes of suicidal behavior, such as impulsivity and aggression, has been reported in healthy adults and psychiatric patients."

JAMA Psychiatry Article

MEDICAL KIDNAPPING

Derya

The woman in this college clip at the end of the reading was diagnosed two years ago with a rare neurological condition known as autoimmune encephalitis. This disease creates antibodies that attack and destroy healthy brain cells. Psychosis, memory loss, hallucinations, movement disorder and problems talking are a few of the presenting symptoms. Usually oral steroids can resolve symptoms within days and had twice before with Derya.

She was scheduled to have IVIG treatment on May 9th. On May 7th, her disease had flared. She was taken to Bellevue Hospital's ER and admitted to neurology for treatment. Bellevue Hospital was given information about Derya's medical history. The hospital was contacted by Derya's Neuro-immunologist to discuss treatment; the psychiatric staff decided to treat with medications they had been told were known to make her condition worse. She was presenting with psychosis; autoimmune encephalitis is known to mimic Bipolar disorder.

Ignoring Derya's medical history and past responses to neuroleptic medications, she was given these medications and worsened within a few hours. On May 10th, the psychiatrist transferred Derya from Neurology to a psych ward where she was put on an involuntary hold and given the diagnosis of Bipolar disorder.

Change.Org Article

Justine Pelletier

'I Wanted To Go Home': Sobbing, Justina Pelletier Describes Boston Children's Psych Ward

The doctors on Pelletier's care team believed her symptoms were largely psychological, rather than due to a rare genetic condition called mitochondrial disease, as her parents believed. The illness affects how cells create energy. Instead, the doctors suspected Pelletier's parents of abuse that might be causing some of her symptoms. So later that day, they moved her to the hospital's locked psychiatric ward.

Lawsuit Hearing Article

Common Mycoplasmas